Review on the formulation and analysis of anti-diabetic agent : Gliclazide
Review on the formulation and analysis of anti-diabetic agent : Gliclazide
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Date
2013-00-00
Authors
A. B. M. Helal Uddin
Mohamed Alaama
Abdualrahman Mohammed Abdualkader
Mohamed B. Awang
Qamar Uddin Ahmed
Syed A. Abbas
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Abstract : Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM)and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to have many other important effects, such as: suppression of platelet functions, antithrombotic actions, decreased the production of tumour necrosis factor (TNF) α by endothelial cells and other effects. The unique activities of gliclazide has open a new avenue for the drug development research. This work is aimed to provide comprehensive information about gliclazide and its current research activities.
Full text access : Research & development Centre, Taylor’s University, Malaysia (e-mail: GTDLSRnD@taylors.edu.my)
Full text access : Research & development Centre, Taylor’s University, Malaysia (e-mail: GTDLSRnD@taylors.edu.my)
Title
Review on the formulation and analysis of anti-diabetic agent : Gliclazide
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A. B. M. Helal Uddin
Mohamed Alaama
Abdualrahman Mohammed Abdualkader
Mohamed B. Awang
Qamar Uddin Ahmed
Syed A. Abbas
Mohamed Alaama
Abdualrahman Mohammed Abdualkader
Mohamed B. Awang
Qamar Uddin Ahmed
Syed A. Abbas
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2013-00-00
Description
Abstract : Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM)and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to have many other important effects, such as: suppression of platelet functions, antithrombotic actions, decreased the production of tumour necrosis factor (TNF) α by endothelial cells and other effects. The unique activities of gliclazide has open a new avenue for the drug development research. This work is aimed to provide comprehensive information about gliclazide and its current research activities.
Full text access : Research & development Centre, Taylor’s University, Malaysia (e-mail: GTDLSRnD@taylors.edu.my)
Full text access : Research & development Centre, Taylor’s University, Malaysia (e-mail: GTDLSRnD@taylors.edu.my)
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Gliclazide
Sulfonylureas
Sulfonylureas
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School of Pharmacy